lamivudine

J - Antiinfectives For Systemic Use -> J05 - Antivirals For Systemic Use -> J05A - Direct Acting Antivirals -> J05AF - Nucleoside And Nucleotide Reverse Transcriptase Inhibitors -> J05AF05 - Lamivudine
Administration category: Free Medicine group: antiviral Brand name: Epivir 3TC

Safety margins

≥ 18 years
WeightROADosage
ROA:
po
Dosage:
min. 150mg 2 dd to max. 300mg 1 dd

Kidney function

≥ 18 years
ROAGFRDosageIntervalComments
ROA: po
GFR:
50 - 80
Dosage:
150 mg 2 dd po
GFR:
30 - 50
Dosage:
startdosis 150 mg, onderhoud 150 mg 1 dd po.
GFR:
15 - 30
Dosage:
startdosis 150 mg, onderhoud 100 mg 1 dd po
GFR:
5 - 15
Dosage:
startdosis 150 mg, onderhoud 50 mg 1 dd po.
GFR:
<5
Dosage:
startdosis 50 mg, onderhoud 25 mg 1 dd po.
Renal elimination: 70%

Renal function-replacement therapy

CAPD: startdosis 50-150 mg, vervolgens 25-50 mg 1x per dag, op geleide van de spiegel

Hemo dialysis: dialized - startdosis 50-150 mg, vervolgens 25-50 mg 1x per dag, op geleide van de spiegel

CAV / VVHD: startdosis 50-150 mg, vervolgens 25-50 mg 1x per dag, op geleide van de spiegel

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-1956.2
Updated: 06/16/2019 - 20:05
Status: Published

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